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Themed collection Coronavirus articles - free to access collection

156 items - Showing page 1 of 3
Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

Zuckerberg, 31, had the best year of all billionaires, having added 11.2billion dollars to his fortune and moving up from number 16 to six on the list. This is Zuckerberg's and Amazon's Jeff Bezos' first appearance in the top ten of Forbes' annual ranking.
库苏马诺教授认为,这一切都表明,苹果正在加大开放度,包括允许开发者对其iOS软件进行更多定制。

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

美国上市交易相比2016年(多年来最疲弱的年份之一)出现起色。根据Dealogic的统计,今年迄今已有112笔IPO得到定价,而去年这个时候只有63笔。发行金额翻了一番多,达到316亿美元。
radiation

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

From the themed collection: 8个词,数尽中国家具8年沉浮
Open Access Perspective

Soft matter science and the COVID-19 pandemic

This assumes, of course, that Apple can find a way to build a $330 iPhone with cheaper parts, a slower processor, a lower resolution screen and perhaps a plastic body, thatisn't, in the phrase Tim Cook used at a Goldman Sachs conference last week, "a crappy product."

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

单词elegant 联想记忆:

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
From the themed collection: 线上线下互动忙 家居卖场花样多
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

在接受《第一财经》采访时,中国建设银行(CCB)董事长提到,中国各银行面对的最大挑战在于不良贷款不断上升。
The Kings also still owe a future first (unprotected in 2019 at worst) to Philly for the honor of being able to sign Rajon Rondo, Kosta Koufos, and Marco Belinelli. Talk about a team with no damn plan.
大多数大宗商品的价格自2016年2月以来有所回升,单位价格的同比降幅已收窄至约5%。
女士们,我们都接到这样的警告,你将会如何回复呢?

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

The need to rebuild supersedes the desire to not give Boston another great pick. That hole has already been dug. Time to crawl out the only way you can: slowly, through smart draft picks, trades, and signings.
最近雇主已经加大招聘力度。劳工部数据显示,10月份新增就业岗位17.1万个,今年以来平均每个月增加15.7万个。这个速度高于去年,并且是2006年以来最强劲的就业增长。[qh]
Columbia Pictures克里斯蒂安?贝尔、艾米?亚当斯和布莱德利?库珀在电影《美国骗局》中早在1月份闹片荒的时候,人们不会想到今年会迎来如此多好电影。不仅如此,有几部影片甚至达到了被我们在心目中理想化了的那些老电影的水准。今年有两部电影脱颍而出。纯娱乐片方面,赢家显然是《美国骗局》(American Hustle),这部由大卫?欧?拉塞尔(David O. Russell)执导的影片讲述了上个世纪七十年代的行骗高手和他们的微妙骗术的故事,幽默诙谐,令人捧腹。而从创新角度看,《地心引力》(Gravity)的全新拍摄技术给观众带来了新的观影体验。人们普遍认为《美国骗局》无可挑剔,这部疯狂喜剧片是一部时代佳作。我个人则认为,《地心引力》是今年的最佳影片。
Hopefully the experts come up with a better plan than one that fell flat earlier this year. The country's tourism body unveiled a 'Beautiful China' logo in February to market the country overseas, but the campaign was mocked for its contrast with the many photos of China's not-so-beautiful cities shrouded in pollution.

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

2012中国创新人物奖中国互联网行业常常被描述成冒牌王国,尤其是对在中国被禁的那些公司的仿冒。中国搜索巨头百度(Baidu Inc.)的网站外观很像谷歌。腾讯的旗舰产品、即时信息服务QQ于1999年以OICQ的名字发布,与当时流行的即时信息服务ICQ功能相似。新浪(Sina Corp.)广受欢迎的微博总是被西方媒体说成“与推特(Twitter)类似”。

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

jewelry

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

A report by human resources website Zhaopin released recently found that only 3.1 percent of students expecting to graduate in July said they will start their own business, down from 6.3 percent in 2015.
抓好金融体制改革。

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

So I don't know what will happen in 2014--and neither does anyone else. What I imagine, though, looks like this:
考试之前,网友通过社交软件,将考试中将要出现的问题和答案截图发布出来。

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
From the themed collection: 中秋小长假楼市告别“金九”
Open Access Review Article

Diagnostic technologies for COVID-19: a review

During the summers, Good Humor ice cream trucks visit the company's campuses every other Friday during lunchtime. In the fall, cider and doughnuts are served twice a month, mid-morning.
Meme-sharing Facebook groups have become a new college tradition, Mic reported last week, with students across the country trading inside jokes and fighting battles with rival universities via screenshot and caption.

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

在P2P贷款领域,借款方被与投资者匹配,后者被鼓励将钱投入放贷,因为他们所得到的回报高于国有银行利息。
中美关系不仅会关系两国利益,而且涉及到地区和世界的和平安全稳定,我们要维护它前行。
Following the devaluation in mid-August, the renminbi rallied in September and October. Devaluation resumed in November, however, and the renminbi closed at its weakest level in three months at 6.4082 to the dollar yesterday. “Since October many countries around China have experienced some capital outflow, and China has had its share,” said Xie Yaxuan, an economist at China Merchants Securities in Shenzhen. “The strengthening dollar is bound to cause some repositioning into dollar assets.”
1.水上类比赛项目

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

Beijing has responded with increasing rancour against Seoul’s decision to deploy Thaad, the Terminal High Altitude Area Defence platform. While South Korea insists the system is for defending itself against North Korean missiles, China fears the technology will allow an ally of the US to spy on its military developments.

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

“We have not really assumed China will get better in the rest of the year,” said James Quincey, Coca-Cola’s chief operating officer. He said juice sales fell double digits in the second quarter in the country and Coca-Cola drinks dropped single digits.
“这可能影响他们一生。”

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

Feng said that the Goal for 2017 is to maintain an overall punctuality rate of about 75%.

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

俄克拉荷马城的经理萨姆-普莱斯蒂并不是截止日交易的陌生人,他送走卡梅罗-佩恩,若弗雷-洛维尔涅和一个二轮签从芝加哥换来泰-吉布森和道格-麦克德莫特的交易大获成功。

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
From the themed collection: 长沙:安居型住房供地将占60%以上
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

Stand: Lenovo CEO Yang Yuanqing shared his $3 million bonus with workers
Snap, however, has sunk to about $15 after initially rallying from its IPO price of $17 in March, damping some expectation of further activity involving so-called decacorns, tech companies that have achieved valuations of $10bn or more through private funding.
这些弊端是很现实的,但是也有很多方法来回避它们。比如说,你可以利用你的谋生工作向雇主展示你努力工作的诚意。并且你也可以在工作之余继续找其他的好工作。
穆里埃塔属于一个叫“五皇后”的黑帮,他们是加州淘金热的高潮期间,臭名昭著的土匪。虽然穆里埃塔的犯罪行为可能没有任何政治色彩,他还是随着来到加州投机的美国定居者,成了墨西哥抵抗的象征。对他而言,这可不是什么好事,而是促使政府悬赏他的人头,导致他被杀和斩首。幸运的是,班德拉斯的角色没有遭到同样的命运。

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

n. 决定,决策
The performance was his worst so far this season, yet, frankly, it wasn't too dissimilar from those that preceded it. In his 20th NBA season, the 37-year-old Bryant has looked his age.
此外,去年共计新增银幕8035块,相当于每一天,都有22块银幕投入使用。现在全国共有大约31627块银幕。
Meanwhile, in recent months mainland investors have been rapidly owning equity trading accounts and putting money into the stock market. The Shanghai Composite has become the region's best performing index, rising nearly 45 per cent year to date.
今年选股遇到困难,部分原因在于市场顶部高度集中。苹果、伯克希尔o哈撒韦、强生、微软和英特尔这五只股票占去了市场涨幅的20%。如果你未持有上述股票,几乎就没有机会分享这场增长盛宴,而正是这几家公司的增长推高了标普500指数。市场上大部分股票的表现要逊色得多。研究公司路佛集团称,标普1500综合指数成分股中,仅有30%的个股跑赢了该指数。上次出现这样的景象,那还是1999年的事。

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

The magazine also notes that he gave $66 million to his presidential campaign and paid $25 million to settle a lawsuit related to Trump University.
2.SpaceX demonstrates a big step towards fully reusable space craft

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

只有资产管理公司利润出现上升,同比增长16.64%,至37.17亿元人民币。

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

有些热门剧已经走得太远,应该降降温了,却仍在大张旗鼓,比如《唐顿庄园》(Downton Abbey)、《丑闻》(Scandal)和《复仇》(Revenge)。ABC频道的新剧《逍遥法外》(How to Get Away With Murder)是一部有趣的替代品,它是一部耸人听闻的夜间肥皂剧,讲述不法辩护律师的故事,简直可以称为“法律与无序”。

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

而相对来说,普遍推出的新限购政策,并未让其他许多最近几个月表现突出的城市受到影响,房价同比依然大幅上涨。
He said game and live-broadcast apps currently hosted by Tencent don't require real-name registration, but the company is considering establishing a platform for parents to monitor their children's behavior.
n. 石油
单词refrigerator 联想记忆:

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

切实落实脱贫攻坚责任制,实施最严格的评估考核,严肃查处假脱贫、“被脱贫”、数字脱贫,确保脱贫得到群众认可、经得起历史检验。
北京一家旅行社向英国《金融时报》展示了一份疑似由中国国家旅游局发出的书面指示。该文件要求旅行社取消预订在3月15日之后成行的组团游,并表示不遵守该指示的企业会被罚款或吊销执照。中国国家旅游局未能马上置评此事。
《宿敌:贝蒂和琼》
The unemployment rate probably won't fall quite as rapidly in 2015, according to economists, especially if more people enter the labor force because jobs are easier to find. Yet another large spate of hiring similar to the gain in 2014 would make the low unemployment rate more believable.

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

作为回应,维尔德斯把吕特归为骗子,指责后者未能遵守在2012年选举期间做出的不支持纾困希腊的承诺。
Emma Thompson, a two-time winner for Howards End and Sense and Sensibility, famously keeps hers in the loo: “They look far too outré anywhere else. They’re great big, gold, shiny things.” She’s not alone – Susan Sarandon, Lionel Richie and Sean Connery all claim to keep their golden fellas alongside their bidets and baths.

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

用这个背带背孩子更加方便舒适。
《一位德国女权主义先锋在痛苦中回顾过去》(A Pioneering German Feminist Looks Back in Anguish)
每一次我们詹姆斯已经达到了顶点,詹姆斯就会拿出更好的表现超过那个顶点。他那无所不包的各项技巧,是詹姆斯辛苦训练的证明。你可以嘲笑他所提发布的所有Instagram录像,但这些都是他仍然能够做到这一点的真正原因;詹姆斯从来不轻视他的每一场比赛,一次都没有。结果便是晚上一次又一次无可比拟的表演。
Baby Driver is so much fun, although it's not necessarily non-stop LOLs, it's definitely non-stop lowercase lols.
谎言3:是的,这挺有道理的。说谎原因:方案二会让我显得毫无头绪。

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

out出去.过时+rage怒气→怒气外露→粗暴,暴行
华尔街、大街上和华盛顿的每一个人都在不断地忘记市场周期的基本原理。请记住:《笑傲股市》(How to Make Money in Stocks)作者、《投资者商务日报》(Investors Business Daily)的比尔?奥尼尔(Bill O'Neill)说,市场的上行周期平均为3.75年,下行周期平均为九个月。
Are you a Type D personality? Test reveals how the little-known character type is so good at bottling up emotions that even they don't realize they're lonely and anxious.

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

201012/119869.shtml重点单词
物理学界这一开拓性的发现已经点燃科学研究的星星之火,而他们的这项研究发展为前沿科技,也不过是时间早晚的事罢了,就像100年前我们无法想象今天的激光和电脑芯片那样,美国物理学会候选会长劳拉?H?格林在接受《纽约时报》采访时表示。

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
From the themed collection: 广州国有建设用地基准地价出炉
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

理由有两方面:首先,从逻辑上讲,你实在有太多的机会被人抓住你在搜索工作。简历的副本会被发现。计算机服务器会被检查。工作伙伴会从表面上或者情绪上(多半是后者)察觉到你为面试而心不在焉。
There's a difference, though, in a team like Miami that's playing its young guys and trying to build a core while taking on losses, and, say, the Magic, who are trying to jump-start a stalled process.
我们首先得明白我们所有人都不知道这次选秀会怎么发展,毕竟大学联赛还在进行。但当所有的这些新鲜的血液都齐聚乐透区,这看起来当然美如画。

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

rob
一部富有感染力的、描写一名年轻黑人男同性恋成长故事的影片《月光男孩》(Moonlight),获得2017年奥斯卡(Oscar)最佳影片奖。不过,该片险些与此奖项擦肩而过,原因是在混乱的颁奖现场,此奖项曾被误颁给了《爱乐之城》(La La Land)。
To be brief, people with type C personalities are perfectionists, consistent and will never break the rules. Unlike their "sister" type A; type C personalities tend to take their time with the details and often check and recheck their work for accuracy. They tend to be deep thinkers and like to know every detail in regards to their work and life.

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

Need to send gigantic files (up to 2gb) quickly? Try WeTransfer.com. You don’t even have to create an account. I use it almost every day.

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

近年来,大多数发达国家的排放量一直在逐步下降,这部分是因为不景气的经济形势,同时也是因为日益加强的气候政策。2013年,由28个国家组成的欧洲联盟(European Union)的排放量下降了1.8%,虽然德国和波兰等几个国家的耗煤量出现增加。英国、意大利和西班牙的排放量显著下降。

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

vaccine
谢亚轩估计,11月中国外储下降的大约40%(350亿美元左右)可归因于欧元和其他货币相对于美元走弱的估值影响,而不是资本外流。

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

It was billed as the year in which female film-makers and women's issues would be in the spotlight. The festival opened with a film by a female director for the first time in 28 years, Isabella Rossellini chaired the Un Certain Regard jury and Salma Hayek convened a high-profile panel to discuss the role of women in cinema. There was plenty to talk about – but had anything really changed? The numbers seemed to speak for themselves: of the 19 films in competition, only two were directed by women. And then came 'Heelgate' – of which, more later… Faced with suggestions that the festival is sexist, artistic director Thierry Frémaux was having none of it. Cannes was being held to an unfairly high standard, he claimed, one not applied to other festivals like Venice or Berlin. His suggestion? Instead, people should “attack the Oscars”.
在你面试应聘者的时候,有些人得分较高,你认为应该他能得到这份工作,但是招聘主管却改掉分数,招那些他喜欢的人。
英国脱欧带来的贸易不确定性
每到仲夏时节,这家企业数据存储公司就会通过举办“狗狗节”来提升士气。员工此时可带着自己的宠物上班,欣赏宠物商品展销会,当地的宠物美容师、宠物商店老板以及驯兽师都会参展,还可以观赏狗狗才艺表演。在“狗狗节”前一周会有一场彩票抽奖活动,全部收入都将捐献给当地的动物慈善机构。

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

Andersl?v, Sweden was plagued by residents with green hair. Johan Pettersson discovered that there was too much copper in their water.
最新名单显示香港大学排名第三,澳门大学排名第六。

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

五大发展理念:创新、协调、绿色、开放、共享的发展理念
“One person quit on Facebook.”

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
From the themed collection: 三四线城市将成橱柜企业布局方向
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

8. It’s never too late to start.

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

‘Episodes’ This comedy on Showtime, too often overlooked, follows the bewilderment of two British TV writers stuck in Hollywood creating a series for Matt LeBlanc, who plays a diva version of himself very convincingly. Not many shows set in the entertainment industry can sustain the conceit, but this is one that got even better in its third year.
The pandas did some tai-chi in Trafalgar Square before kicking on at a panda party in Convent Garden as part of the first ever Panda Awareness Week.
adj. 社会的,社交的
Although Facebook is blocked in China, Tencent has linked WeChat to Facebook, which means that users outside of China can use the service in conjunction with the world's most popular social network. That is a boon for WeChat in Southeast Asian countries like Indonesia, Thailand and the Philippines, which have large numbers of Facebook users. Tencent has offered WeChat in languages for all three markets.

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

据牛津经济研究院(Oxford Economics)估算,若剔除价格影响,中国10月进口量同比降幅为2.6%。
vi. 获得奖章

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

According to Putin's most recent income declaration, he earned roughly 8.9 million rubles ($137,000) in 2015.
为保证更快的经济增长就必须要要消除美联储所担忧的另一个恶魔:通货紧缩,或者说价格下降。Baumohl 称“经济增长达到3%以上,并且自90年代以来新增了大量工作的国家发生通货紧缩几乎是不可能的”。
Neighborhoods

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
From the themed collection: 武汉家居大牌时代加速来临
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

[si'vi?]
Investors in emerging markets need no reminder of the importance for EM assets of the US Federal Reserve — or do they?
[str?uk]

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

待售房产:一栋带有四间卧室与四间半浴室的希腊复兴式房屋
[s?'plai]

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
From the themed collection: 互联网+ 成为卫浴行业新出路
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
From the themed collection: 2015年建材行业大事记:去产能
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

我们不希望通过贬值来增加出口,这不利于企业转型升级。
1.哥吃的不是面,是寂寞。
某种程度上,这种借鉴是基于这样的假设:把一种时装风格从它自身的环境中剥离出来,就能同时去除它所有潜在的负面寓意:譬如战争和王朝。它会变成一种独立存在的审美形式,不再象征任何复杂的社会和政治动荡。

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
From the themed collection: 信托业加速转型服务实体经济
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

这部20世纪70年代黑色幽默犯罪电影的主角,是诈骗高手欧文·罗森菲尔德和他的情妇西德尼·普鲁塞尔,他们被一名联邦调查局(FBI)干员抓获,然后被迫欺骗腐败的政治家。二人继续与干员、政治家目标以及自己的家人周旋,最终达成豁免协议,得以不受任何刑事指控就脱离苦海。
这家瑞士学校在2016年全球90个最佳管理学硕士项目中荣登榜首,连续6年夺冠。

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

When Tom Ravenscroft left Oxford university with a degree in econ-om-ics and management in 2007, he wanted to be a management consultant. He even had a job offer from Oliver Wyman, following an internship. “I had no career vision beyond going into business. It was a very hazy concept,” he says.
在法国商学院当中,图卢兹商学院(Toulouse Business School)的进步最大,上升了14位,原因是该商学院首次进入了EMBA榜单。
贷款的条件不仅仅只局限于裸照。同样被泄露的还有大量疑似借贷双方对话的屏幕截图,一个贷款人要求女学生提供自己的自慰视频。

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

Others who made the top ten include Amazon's Jeff Bezos at fifth on the list, Mark Zuckerberg of Facebook at sixth, Oracle's Larry Ellison at seventh, Michael Bloomberg at eighth, and tied for ninth are David and Charles Koch.

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

Miranda Lambert “Bathroom Sink” (RCA Nashville)
The special tokens of appreciation will take place alongside more traditional and somber observances, including the laying of a wreath by President Barack Obama at the Tomb of the Unknown Soldier at Arlington National Cemetery, just across the Potomac River from the nation's capital.

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

在所有这些影片中,斯文顿用的是同一个牙齿设计专家——伦敦Fangs F/X公司的克里斯·莱昂斯(Chris Lyons)。他在工作中设计了各种牙齿,包括为坎耶·韦斯特(Kanye West)一个音乐录影带中的一只杜宾犬设计了金色尖牙。
ordering

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

"We have searched for Richard and we have found him. Now it's time to honour him," she said.
单词institute 联想记忆:

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
From the themed collection: 家居行业 “阵痛”中求变寻新机
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

“This young Vermonter clearly has an interest in service and anyone putting ideas forward with the goal of making Vermont a better place is appreciated here,” Scott's spokeswoman, Rebecca Kelley, tells PEOPLE.
[kɑ:st]

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

凯莉·克莱森、蒂姆·麦格罗、泰勒·斯威夫特、凯莉·安德伍德、米兰达·兰伯特等人的现场表演high翻了米高梅大花园露天剧场。

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
From the themed collection: 保定17宗地块挂牌出让
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

The parallels between Snapchat, the upstart "sexting" service, and social media behemoth Facebook (FB) in its early days are uncanny. We all know how well Zuckerberg's long bet paid off (not to mention how thoroughly he vanquished those dastardly Winklevoss twins). Could Snapchat's future be just as bright?
The best bosses understand the art of delegation. My commenter said something along the lines of, “They’ve fired themselves from their previous job,” meaning that they don’t interfere in the day-to-day and minute-to-minute workflow or processes. In essence, learning to delegate instead of micromanage is about trust。
《橘色》,导演:肖恩·贝克(Sean Baker)。
这些人工眼睛,确实恢复了盲鼠的视力。猴子的视网膜工作原理和人类的非常相似,因此随后在猴子上进行的试验给了最终的人类试验以成功的希望。

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

French business schools top the 2017 ranking. Edhec Business School, based in Lille and Nice, leads the field for the first time. HEC Paris, which dominated this ranking since its first edition in 2011, drops to second place.

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

Index: 97.8
蒋依依说,2013年人民币兑美元汇率上涨近3%,使北京成为了一个更加昂贵的旅游目的地。
美国品牌如Chipotle、德克萨斯仪器公司和通用动力第一次出现在了该榜单上。

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

I hope you have a most happy and prosperous New Year.
We Pay Attention … Selectively

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

An evaluation report on the "Double Eleven" (singles' day) shopping spree has been released in Beijing, offering insights into China's largest annual online shopping event.
It is the first biography to win the prize, although Mr Greenspan’s autobiography, The Age of Turbulence, was shortlisted in 2007, the year before the financial crisis raised serious questions about the central banker’s legacy.

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

And, thanks to Artnet and other databases that list auction results, wealthy people who buy art have become all too aware of how hard it is to make a profit on old masters.

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

对欧盟、日本和香港(香港是中国向世界其它很多地区出口的一个中转站)出口分别下跌4.1%、9.5%和12.2%。
Baoneng’s raid has been bitterly resisted by Wang Shi, Vanke’s founder who has sought out white knights in a so far successful effort to retain control of the management-led company. The takeover battle fuelled a surge both in the price of Vanke’s Shenzhen-traded shares and Mr Yao’s known worth.
超级大坏蛋们将受命保护人类——这就是《自杀小队》的主旨。 一个名叫“A.R.G.U.S”的政府机构招募了一些罪犯帮它执行危险任务,罪犯们将得到的报酬是减刑。这支特遣小队的成员有小丑、死亡射手、哈利·奎恩、回旋镖队长、杀人鳄以及DC漫画宇宙里的其他坏家伙。

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

6. 减少饱和脂肪摄入可以帮助保持记忆力
此外,这也是北京大学连续第二年在亚洲大学排行榜上排名第二位。
2. 米拉?库妮丝
The BFC's news has been met with support from people on social media, who have applauded the designers choosing to forgo the use of animal fur.

Graphical abstract: Length-scale dependence of protein hydration-shell density
From the themed collection: 2016年LED产业现微增长趋势
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

这款甜点有金色叶子,以香槟调味,单价为100美元。
Following the devaluation in mid-August, the renminbi rallied in September and October. Devaluation resumed in November, however, and the renminbi closed at its weakest level in three months at 6.4082 to the dollar yesterday. “Since October many countries around China have experienced some capital outflow, and China has had its share,” said Xie Yaxuan, an economist at China Merchants Securities in Shenzhen. “The strengthening dollar is bound to cause some repositioning into dollar assets.”

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

单词flimsy 联想记忆:
Now that Chris and his girlfriend, Rose, have reached the meet-the-parents milestone of dating, she invites him for a weekend getaway upstate with Missy and Dean. At first, Chris reads the family's overly accommodating behavior as nervous attempts to deal with their daughter's interracial relationship, but as the weekend progresses, a series of increasingly disturbing discoveries lead him to a truth that he never could have imagined.
4.不推崇微化管理

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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About this collection

Derrick Rose
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